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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VDR
All Species:
19.39
Human Site:
S125
Identified Species:
47.41
UniProt:
P11473
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11473
NP_000367.1
427
48289
S125
D
S
L
R
P
K
L
S
E
E
Q
Q
R
I
I
Chimpanzee
Pan troglodytes
A2T7D9
348
39540
R77
K
C
L
D
A
G
M
R
K
D
M
I
L
S
A
Rhesus Macaque
Macaca mulatta
Q8SQ01
434
49974
R127
E
R
R
A
L
I
K
R
K
K
R
E
R
I
G
Dog
Lupus familis
XP_543714
448
49978
S146
D
S
L
R
P
K
L
S
E
E
Q
Q
R
I
I
Cat
Felis silvestris
Mouse
Mus musculus
P48281
422
47833
L124
K
D
S
L
R
P
K
L
S
E
E
Q
Q
H
I
Rat
Rattus norvegicus
P13053
423
47795
S125
D
S
L
R
P
K
L
S
E
E
Q
Q
H
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O42392
451
51281
S148
E
S
L
K
P
K
L
S
E
E
Q
Q
K
V
I
Frog
Xenopus laevis
O13124
422
48170
R122
E
A
L
K
E
S
M
R
P
K
I
S
D
E
Q
Zebra Danio
Brachydanio rerio
Q9PTN2
453
50848
S157
E
A
R
K
P
R
L
S
D
E
Q
M
Q
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123279
490
55735
S195
I
D
Q
S
P
Q
Q
S
E
E
E
S
I
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.1
39.8
88.3
N.A.
88.5
89.6
N.A.
N.A.
76
73.3
67.9
N.A.
N.A.
N.A.
N.A.
30.2
Protein Similarity:
100
51.9
56.2
91.7
N.A.
93.2
93.4
N.A.
N.A.
84.4
85
78.8
N.A.
N.A.
N.A.
N.A.
48.7
P-Site Identity:
100
6.6
13.3
100
N.A.
20
93.3
N.A.
N.A.
73.3
6.6
46.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
26.6
46.6
100
N.A.
33.3
93.3
N.A.
N.A.
100
40
86.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
10
10
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
30
20
0
10
0
0
0
0
10
10
0
0
10
0
0
% D
% Glu:
40
0
0
0
10
0
0
0
50
70
20
10
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% H
% Ile:
10
0
0
0
0
10
0
0
0
0
10
10
10
50
60
% I
% Lys:
20
0
0
30
0
40
20
0
20
20
0
0
10
0
0
% K
% Leu:
0
0
60
10
10
0
50
10
0
0
0
0
10
0
10
% L
% Met:
0
0
0
0
0
0
20
0
0
0
10
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
60
10
0
0
10
0
0
0
0
10
0
% P
% Gln:
0
0
10
0
0
10
10
0
0
0
50
50
20
0
10
% Q
% Arg:
0
10
20
30
10
10
0
30
0
0
10
0
30
0
0
% R
% Ser:
0
40
10
10
0
10
0
60
10
0
0
20
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _